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KMID : 0352120220370010021
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Journal of Kyung Hee University
2022 Volume.37 No. 1 p.21 ~ p.24
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Development of Delayed Anaphylactic Reaction after Sugammadex Administration in the Post-Anesthesia Care Unit
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Kim Ga-Hee
Lee Jun-Bum
Lee Sang-Ho
Choi Jeong-Hyun
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Abstract
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Sugammadex induced anaphylactic reaction is very urgent event as it is usually not anticipated in the advance. The incidence of anaphylactic reaction due to sugammadex is rare, 0.0039% to 0.3%, but it can occur even if there is no previous allergy history, and it often occurs after extubation, so immediate diagnosis and treatment are essential. This report presents a 70-year-old woman who had no previous exposure to sugammadex and allergy history and scheduled to undergo posterior lumbar interbody fusion L4-S1 to treat lumbosacral spondylolisthesis. Anesthesia via propofol, inhalational gas, remifentanil and rocuronium was used. The operation under general anesthesia went well without any problems The patient was administered sugammadex to reversal neuromuscular block, and delivered to post-anesthesia care unit (PACU). After arrival at PACU, she had anaphylactic reaction and received appropriate treatment including epinephrine. She discharged without any complications 6 weeks days after the surgery.
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KEYWORD
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Sugammadex, Anaphylactic reaction, Gamma dextrin derivative, Neuromuscular blocking agent, Epinephrine
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